Matrix metalloproteinase activities in avian tibial dyschondroplasia

Gene expression and tibial dyschondroplasia.

Tibial dyschondroplasia (TD) is a skeletal deformity associated with rapid growth in a number of avian species. The disease is the result of a disruption in the cascade of events that occur in the epiphyseal growth plate. Whereas the incidence of TD is susceptible to genetic selection, no specific genetic defect has been identified. Although there are extensive data describing the morphological...

Tibial dyschondroplasia, a cartilage abnormality in poultry

Gambogic Acid Inhibits Hsp90 Expressions in Thiram-Induced Tibial Dyschondroplasia

Received: Revised: Accepted: Published online: March 26, 2015 July 23, 2015 August 25, 2015 December 31, 2015 Tibial Dyschondroplasia (TD) is an important leg problem in fast growing birds that disturbs the proximal tibial growth plate. A study was conducted to evaluate the effects of gambogic acid (GA) on hsp-90 expressions and antioxidant capability in thiram-induced TD chicken. One hundred a...

Changes in Serum Protein Profiles of Chickens with Tibial Dyschondroplasia

Differences in serum protein profiles were analyzed to identify possible biomarkers associated with a poultry leg problem named tibial dyschondroplasia (TD) that can lead to lameness. A bead-based affinity matrix (ProteoMiner TM ) containing a combinatorial library of hexapeptides was used to deplete high abundant proteins and enrich the less abundant ones to compare between the sera of six-wee...

Induction of tibial dyschondroplasia in turkeys by tetramethylthiuram disulfide (thiram).

Tibial dyschondroplasia (TD) is a prevalent skeletal abnormality associated with rapid growth rate in many avian species; it causes enormous economic losses and is an animal welfare problem. Tibial dyschondroplasia is characterized by the presence of a nonvascularized, nonmineralized lesion that extends from the epiphyseal growth plate into the metaphysis of the proximal tibiotarsal bones. The ...